SCHEMBL10744667

SCHEMBL10744667

SCCOCCOCCOCCS.c1ccc2c(c1)NSS2.c1ccc2c(c1)NSS2

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
BCHE P06276 1/20 0.31
POLB P06746 1/20 0.31
CYP3A4 P08684 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
MAOA P21397 1/20 0.31
CNR1 P21554 1/20 0.31
ACHE P22303 1/20 0.31
PTGS1 P23219 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
PTGS2 P35354 1/20 0.31
SNCA P37840 1/20 0.31
SLC6A3 Q01959 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28634564 0.80 GAA (0.41) MEN1CYP1A2BCHEPOLBCYP3A4
SCHEMBL30839394 0.80
SCHEMBL995222 0.80
Hydrochloric Acid SCHEMBL11290802 0.78 GAA (0.42) MEN1CYP1A2BCHEPOLBCYP3A4
SCHEMBL29603084 0.78 GAA (0.42) MEN1CYP1A2BCHEPOLBCYP3A4
SCHEMBL11661689 0.61 HDAC3 (0.61) TDP1
SCHEMBL26364546 0.61 HDAC3 (0.61) TDP1
SCHEMBL25256307 0.61 MEN1 (0.38) MEN1KMT2A
SCHEMBL5081800 0.61 MEN1 (0.38) MEN1KMT2A
SCHEMBL17006458 0.61 MEN1 (0.38) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62100542-A None JP disclosed
JP-S62100542-A VULCANIZING ACCELERATOR FOR RUBBER KAWAGUCHI KAGAKU KOGYO KK 1987-05-11 JP disclosed