Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 8/20 | 0.57 |
| ▸ | DRD5 | P21918 | 6/20 | 0.57 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 9/20 | 0.47 |
| ▸ | HTR2A | P28223 | 9/20 | 0.45 |
| ▸ | HTR2B | P41595 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.43 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.43 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.43 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.43 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.43 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.43 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.43 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10747041 | 0.89 | DRD1 (0.71) | DRD1DRD5ADCY5KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL10745663 | 0.88 | DRD1 (0.69) | DRD1DRD5ADCY5KDM4EMAPT | |
| SCHEMBL10748210 | 0.85 | DRD1 (0.67) | DRD1DRD5ADCY5HTR2AKDM4E | |
| Hydrochloric Acid SCHEMBL10744987 | 0.84 | DRD1 (0.66) | DRD1DRD5ADCY5HTR2AKDM4E | |
| SCHEMBL10345635 | 0.83 | HTR2C (0.64) | DRD1DRD5ADCY5HTR2CHTR2A | |
| SCHEMBL10345668 | 0.83 | DRD1 (0.57) | DRD1DRD5ADCY5KDM4EMAPT | |
| SCHEMBL11609656 | 0.82 | DRD1 (0.60) | DRD1DRD5ADCY5HTR2CHTR2A | |
| SCHEMBL10748260 | 0.82 | DRD1 (0.57) | DRD1DRD5ADCY5HTR2CHTR2A | |
| SCHEMBL10747314 | 0.80 | DRD1 (0.55) | DRD1DRD5ADCY5HTR2CHTR2A | |
| SCHEMBL7320752 | 0.76 | DRD1 (0.81) | DRD1DRD5ADCY5KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244088-A2 | 1-Phenyl-3-benzazepine compounds and medicaments containing these compounds for treating gastrointestinal motility disorders | SMITHKLINE BEECHAM CORPORATION (US) | 1987-11-04 | — | — | EP | disclosed |