Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.50 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 3/20 | 0.49 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10746220 | 1.00 | CYP3A4 (0.50) | CYP3A4MEN1USP2ALDH1A1LMNA | |
| SCHEMBL10355270 | 0.96 | CYP3A4 (0.52) | CYP3A4MEN1USP2ALDH1A1LMNA | |
| SCHEMBL9752271 | 0.96 | CYP3A4 (0.52) | CYP3A4MEN1USP2ALDH1A1LMNA | |
| SCHEMBL10481180 | 0.96 | CYP3A4 (0.52) | CYP3A4MEN1USP2ALDH1A1LMNA | |
| SCHEMBL10481197 | 0.96 | CYP3A4 (0.52) | CYP3A4MEN1USP2ALDH1A1LMNA | |
| SCHEMBL9229935 | 0.94 | CYP3A4 (0.53) | CYP3A4MEN1USP2ALDH1A1LMNA | |
| SCHEMBL9227505 | 0.93 | CYP3A4 (0.51) | CYP3A4MEN1USP2ALDH1A1LMNA | |
| SCHEMBL10709063 | 0.93 | RARB (0.50) | CYP3A4MEN1USP2ALDH1A1LMNA | |
| SCHEMBL10748461 | 0.93 | RARB (0.50) | CYP3A4MEN1USP2ALDH1A1LMNA | |
| SCHEMBL10709053 | 0.93 | RARB (0.50) | CYP3A4MEN1USP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4676925-A | Liquid crystalline biphenyl derivatives and mixtures thereof | CHISSO CORPORATION (JP) | 1987-06-30 | — | — | US | disclosed |
| EP-0131373-B1 | LIQUID CRYSTALLINE BIPHENYL DERIVATIVES AND MIXTURES THEREOF | Chisso Corporation (JP) | 1986-12-30 | — | — | EP | disclosed |
| US-4614609-A | FERROELECTRICITY; DISPLAY ELEMENTS | CHISSO CORPORATION (JP) | 1986-09-30 | — | — | US | disclosed |
| EP-0131373-A1 | Liquid crystalline biphenyl derivatives and mixtures thereof | Chisso Corporation (JP) | 1985-01-16 | — | — | EP | disclosed |