SCHEMBL1074667

SCHEMBL1074667

CCOC(=O)C[C@H](N)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 9/20 0.50
GRIA4 P48058 3/20 0.47
GRIK3 Q13003 3/20 0.47
GRIK5 Q16478 3/20 0.47
SLC1A1 P43005 5/20 0.47
SLC1A3 P43003 4/20 0.47
SLC1A2 P43004 4/20 0.47
SLC7A5 Q01650 1/20 0.46
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
GRIK2 Q13002 6/20 0.46
GRM1 Q13255 1/20 0.43
GRM2 Q14416 1/20 0.43
TRPA1 O75762 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CYP1A2 P05177 1/20 0.42
GRIA2 P42262 2/20 0.41
GRIA1 P42261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1844883 1.00 GRIK1 (0.50) GRIK1GRIA4GRIK3GRIK5SLC1A1
SCHEMBL10513370 1.00 GRIK1 (0.50) GRIK1GRIA4GRIK3GRIK5SLC1A1
Hydrochloric Acid SCHEMBL21246725 0.98 GRIK1 (0.48) GRIK1GRIA4GRIK3GRIK5SLC1A1
SCHEMBL1172846 0.84 MGAM (0.48) MGAMGAASIMGAM2TRPA1
SCHEMBL30722280 0.84 MGAM (0.48) MGAMGAASIMGAM2TRPA1
SCHEMBL1172849 0.84 MGAM (0.48) MGAMGAASIMGAM2TRPA1
SCHEMBL2617390 0.84 MGAM (0.48) MGAMGAASIMGAM2TRPA1
SCHEMBL14456726 0.84 MGAM (0.50) GRIK1GRIA4GRIK3GRIK5SLC1A1
SCHEMBL25491149 0.84 GRIK1 (0.48) GRIK1GRIA4GRIK3GRIK5SLC1A1
Cyclohexylamine SCHEMBL5689389 0.83 GRIK1 (0.43) GRIK1GRIA4GRIK3GRIK5SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11905527-B2 Gel composition for culturing cells, production method thereof, method for culturing cells, and substrate for culturing cells SHIMADZU CORPORATION (JP) 2024-02-20 US claimed
CN-115304516-A Compounds with unconventional chromophores, their preparation and use 四川大学 2022-11-08 CN claimed
CN-104937041-B Method for preparing self-dispersing pigment 纳幕尔杜邦公司 2017-10-27 CN claimed
CN-104919008-B Method for preparing the silica containing self-dispersing pigment of bag 纳幕尔杜邦公司 2017-07-18 CN claimed
US-5250517-A Hypotensive and cardiotonic agents; cardiac insufficiency HOFFMANN-LA ROCHE INC. (US) 1993-10-05 US claimed
US-20250177383-A1 DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. 2025-06-05 US disclosed
CN-120040435-A Mangiferin and derivatives thereof, preparation method and medical application thereof 安徽中医药大学 2025-05-27 CN disclosed
US-20250035616-A1 Organoid Compositions SHIMADZU CORPORATION (JP) 2025-01-30 US disclosed
EP-4482823-A1 DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF Dice Alpha, Inc. (US) 2025-01-01 EP disclosed
US-20240399776-A1 COLOR DEVELOPER, THERMAL RECORDING MATERIAL, AND THERMAL RECORDING LAYER COATING MATERIAL SANKO CO., LTD. (JP) 2024-12-05 US disclosed
CN-115304516-B Compounds with unconventional chromophores, their preparation and use 四川大学 2024-04-30 CN disclosed
US-11905527-B2 Gel composition for culturing cells, production method thereof, method for culturing cells, and substrate for culturing cells SHIMADZU CORPORATION (JP) 2024-02-20 US disclosed
WO-1998029419-A1 CYANOPHOSPHORUS COMPOUNDS AND THEIR PREPARATION MONSANTO COMPANY (US) 1998-07-09 WO disclosed
WO-1998029422-A1 CYANOPHOSPHONATE DERIVATIVES MONSANTO COMPANY (US) 1998-07-09 WO disclosed
EP-0770057-A1 METHOD FOR PRODUCING CALCIUM SALTS OF [S,S]-ETHYLENEDIAMINE-N,N'-DISUCCINIC ACID ALBEMARLE CORPORATION (US) 1997-05-02 EP disclosed
US-5550285-A Method for producing calcium salts of [S,S]-ethylenediamine-N,N'-disuccinic acid ALBEMARLE CORPORATION 1996-08-27 US disclosed
WO-1996001804-A1 METHOD FOR PRODUCING CALCIUM SALTS OF [S,S]-ETHYLENEDIAMINE-N,N'-DISUCCINIC ACID ALBEMARLE CORPORATION (US) 1996-01-25 WO disclosed
US-5278148-A Hypotensive agents HOFFMANN-LA ROCHE INC. (US) 1994-01-11 US disclosed
US-5250517-A Hypotensive and cardiotonic agents; cardiac insufficiency HOFFMANN-LA ROCHE INC. (US) 1993-10-05 US disclosed
US-5140011-A Hypotensive agents HOFFMANN-LA ROCHE, INC. (US) 1992-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250177383-A1 DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF IL17A, IL23R, IL2 GRIK1 4116/4885GRIA4 3867/4885GRIK3 4238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.