SCHEMBL10746705

SCHEMBL10746705

CCCCCCCCCCCC=Cc1ccccc1CCC(=O)OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 2/20 0.48
CYSLTR1 Q9Y271 2/20 0.48
SOAT2 O75908 1/20 0.45
SOAT1 P35610 1/20 0.45
EPHX2 P34913 5/20 0.43
FAAH O00519 2/20 0.43
PPARG P37231 1/20 0.43
ALOX5 P09917 2/20 0.43
MMP2 P08253 2/20 0.43
F7 P08709 2/20 0.43
F3 P13726 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.43
ALOX15 P16050 1/20 0.43
ECE1 P42892 1/20 0.43
SGMS1 Q86VZ5 1/20 0.43
SGMS2 Q8NHU3 1/20 0.43
MUS81 Q96NY9 1/20 0.43
HSD17B10 Q99714 1/20 0.43
SAE1 Q9UBE0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10746693 1.00 CYSLTR2 (0.48) CYSLTR2CYSLTR1SOAT2SOAT1EPHX2
SCHEMBL25713055 0.93 EPHX2 (0.48) CYSLTR2CYSLTR1SOAT2SOAT1EPHX2
SCHEMBL31348947 0.93 EPHX2 (0.48) CYSLTR2CYSLTR1SOAT2SOAT1EPHX2
SCHEMBL25713054 0.93 EPHX2 (0.48) CYSLTR2CYSLTR1SOAT2SOAT1EPHX2
SCHEMBL10519228 0.91 PPARG (0.47) CYSLTR2CYSLTR1EPHX2PPARGALOX5
SCHEMBL9801991 0.91 PPARG (0.47) CYSLTR2CYSLTR1EPHX2PPARGALOX5
SCHEMBL10794770 0.87 PPARG (0.52) CYSLTR2CYSLTR1SOAT2SOAT1EPHX2
SCHEMBL10794771 0.87 PPARG (0.52) CYSLTR2CYSLTR1SOAT2SOAT1EPHX2
SCHEMBL10738954 0.86 CYSLTR2 (0.60) CYSLTR2CYSLTR1EPHX2FAAHPPARG
SCHEMBL10738945 0.86 CYSLTR2 (0.60) CYSLTR2CYSLTR1EPHX2FAAHPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4713486-A ANTIALLERGENS BEECHAM GROUP P.L.C. (GB) 1987-12-15 US disclosed
EP-0109225-B1 ARACHIDONIC ACID ANALOGUES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINE BEECHAM GROUP PLC (GB) 1985-08-28 EP disclosed