SCHEMBL10747735

SCHEMBL10747735

[CH2]Sc1cccc(O)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31281467 0.79 CA12 (0.58)
SCHEMBL31123642 0.79 HSD17B10 (0.58)
SCHEMBL30183570 0.79 HSD17B10 (0.58)
SCHEMBL2239504 0.79 CA12 (0.58)
SCHEMBL145253 0.79 HSD17B10 (0.58)
SCHEMBL7188199 0.75
SCHEMBL8138438 0.75
SCHEMBL7188832 0.75
SCHEMBL9985105 0.75
SCHEMBL30357035 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4698338-A ANTIBIOTICS ELI LILLY AND COMPANY (US) 1987-10-06 US disclosed
EP-0233780-A2 O-substituted oximino cephalosporins ELI LILLY AND COMPANY (US) 1987-08-26 EP disclosed
EP-0095836-B1 AZA-FUROCHROMONES THE UPJOHN COMPANY (US) 1986-08-13 EP disclosed
EP-0099172-B1 6,7-DIHYDRO-7,7-DISUBSTITUTED-KHELLINS THE UPJOHN COMPANY (US) 1986-08-06 EP disclosed
US-4434295-A Anti-atherosclerotic 6,7-dihydro-7,7-disubstituted-khellin analogs THE UPJOHN COMPANY (US) 1984-02-28 US disclosed
EP-0099172-A1 6,7-Dihydro-7,7-disubstituted-khellins THE UPJOHN COMPANY (US) 1984-01-25 EP disclosed
EP-0095836-A1 Aza-furochromones THE UPJOHN COMPANY (US) 1983-12-07 EP disclosed
US-4412071-A Antiatherosclerotic compositions THE UPJOHN COMPANY (US) 1983-10-25 US disclosed