SCHEMBL10748423

SCHEMBL10748423

CC(C)(C)NS(=O)(=O)n1cc(N)cn1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 2/20 0.32
PIK3CG P48736 3/20 0.32
PIK3CD O00329 2/20 0.32
PIK3CB P42338 2/20 0.32
PIK3CA P42336 1/20 0.32
ALDH1A1 P00352 1/20 0.31
ALOX5AP P20292 2/20 0.30
FEN1 P39748 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1663043 0.74 F2 (0.35) ALDH1A1
SCHEMBL17076738 0.71 MAPT (0.35) ALDH1A1
SCHEMBL10768598 0.69 NSD2 (0.35) NSD2PIK3CGPIK3CDPIK3CBPIK3CA
SCHEMBL10735202 0.66 GAA (0.39)
SCHEMBL16812317 0.63 NPC1 (0.43) ALDH1A1ALOX5AP
SCHEMBL16423182 0.62 KIT (0.35)
SCHEMBL573656 0.61 MAPT (0.33) ALDH1A1
SCHEMBL16604766 0.61 KDM1A (0.43) ALDH1A1
SCHEMBL21199568 0.61 MAPT (0.43) ALDH1A1
Hydrochloric Acid SCHEMBL16052430 0.60 KDM1A (0.43) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4707178-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-11-17 US disclosed
US-4655817-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-07 US disclosed