Tetrabuthylammonium

Tetrabuthylammonium

SCHEMBL10748554

CCCC[N+](CCCC)(CCCC)CCCC.O=C(O)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A1 O15245 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.42
PKM P14618 1/20 0.42
SLC22A2 O15244 1/20 0.41
HCAR2 Q8TDS4 1/20 0.40
ESR1 P03372 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
TAS1R2 Q8TE23 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38
HIF1A Q16665 1/20 0.38
HSD17B10 Q99714 1/20 0.38
BID P55957 3/20 0.36
MCL1 Q07820 3/20 0.36
BCL2L1 Q07817 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrabuthylammonium SCHEMBL10529065 0.83 SLC22A1 (0.44) SLC22A1SMN1; SMN2PKMSLC22A2ESR1
SCHEMBL28549816 0.79 HCAR2 (0.39) HCAR2ESR1ALDH1A1ALOX15TSHR
Tetrabuthylammonium SCHEMBL29047726 0.76 SLC22A1 (0.71) SLC22A1SMN1; SMN2SLC22A2ESR1ALDH1A1
Tetrabuthylammonium SCHEMBL109268 0.76 SLC22A1 (0.71) SLC22A1SMN1; SMN2SLC22A2ESR1ALDH1A1
Butylamine SCHEMBL9766876 0.74 HCAR2 (0.41) SMN1; SMN2PKMHCAR2ESR1TAS1R3
Tetrabuthylammonium SCHEMBL16343544 0.74 SLC22A1 (0.67) SLC22A1SMN1; SMN2SLC22A2ESR1ALDH1A1
Tetrabuthylammonium SCHEMBL6356120 0.74 SLC22A1 (0.67) SLC22A1SMN1; SMN2SLC22A2ESR1ALDH1A1
Tetrabuthylammonium SCHEMBL29241995 0.74 SLC22A1 (0.67) SLC22A1SMN1; SMN2SLC22A2ESR1ALDH1A1
Tetrabuthylammonium SCHEMBL21372576 0.74 SLC22A1 (0.67) SLC22A1SMN1; SMN2SLC22A2ESR1ALDH1A1
Alcohol SCHEMBL29191762 0.74 SMN1; SMN2 (0.43) SMN1; SMN2PKMHCAR2ESR1TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4652657-A Chiral rhodium-diphosphine complexes HOFFMANN-LA ROCHE INC. (US) 1987-03-24 US disclosed