Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31368119 | 0.76 | KDM1A (0.43) | KDM1AMAOBKMT2AL3MBTL1CCR5 | |
| SCHEMBL31368071 | 0.76 | KDM1A (0.43) | KDM1AMAOBKMT2AL3MBTL1CCR5 | |
| SCHEMBL2183100 | 0.75 | KDM1A (0.41) | KDM1AMAOBKMT2AL3MBTL1CCR5 | |
| SCHEMBL19180749 | 0.74 | KDM1A (0.50) | KDM1AMAOBKMT2AL3MBTL1MAOA | |
| SCHEMBL9383617 | 0.74 | TLR2 (0.48) | KDM1AMAOBKMT2AL3MBTL1USP30 | |
| SCHEMBL9383626 | 0.74 | TLR2 (0.48) | KDM1AMAOBKMT2AL3MBTL1USP30 | |
| SCHEMBL9270099 | 0.74 | TLR2 (0.48) | KDM1AMAOBKMT2AL3MBTL1USP30 | |
| SCHEMBL9270085 | 0.74 | TLR2 (0.48) | KDM1AMAOBKMT2AL3MBTL1USP30 | |
| SCHEMBL5627069 | 0.74 | KDM1A (0.39) | KDM1AMAOBKMT2AL3MBTL1CCR5 | |
| SCHEMBL14441187 | 0.74 | KDM1A (0.39) | KDM1AMAOBKMT2AL3MBTL1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0208210-A1 | Pyridonecarboxylic acid derivatives and process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-01-14 | — | — | EP | disclosed |