Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.71 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.68 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.68 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.59 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.52 |
| ▸ | TLR2 | O60603 | 3/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.47 |
| ▸ | LPAR6 | P43657 | 5/20 | 0.47 |
| ▸ | LPAR4 | Q99677 | 5/20 | 0.47 |
| ▸ | P2RY10 | O00398 | 2/20 | 0.46 |
| ▸ | AKT1 | P31749 | 2/20 | 0.45 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.45 |
| ▸ | AKT2 | P31751 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.45 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608015 | 1.00 | PLA2G2C (0.71) | PLA2G2CLPAR1LPAR3LPAR2PLA2G2D | |
| SCHEMBL12506212 | 1.00 | PLA2G2C (0.71) | PLA2G2CLPAR1LPAR3LPAR2PLA2G2D | |
| SCHEMBL23300849 | 0.99 | PLA2G2C (0.73) | PLA2G2CLPAR1LPAR3LPAR2PLA2G2D | |
| SCHEMBL21568785 | 0.99 | PLA2G2C (0.73) | PLA2G2CLPAR1LPAR3LPAR2PLA2G2D | |
| SCHEMBL28622692 | 0.99 | PLA2G2C (0.73) | PLA2G2CLPAR1LPAR3LPAR2PLA2G2D | |
| SCHEMBL25394384 | 0.99 | PLA2G2C (0.73) | PLA2G2CLPAR1LPAR3LPAR2PLA2G2D | |
| SCHEMBL931685 | 0.99 | PLA2G2C (0.73) | PLA2G2CLPAR1LPAR3LPAR2PLA2G2D | |
| SCHEMBL22092476 | 0.99 | PLA2G2C (0.73) | PLA2G2CLPAR1LPAR3LPAR2PLA2G2D | |
| SCHEMBL2702607 | 0.99 | PLA2G2C (0.73) | PLA2G2CLPAR1LPAR3LPAR2PLA2G2D | |
| SCHEMBL28781558 | 0.99 | PLA2G2C (0.73) | PLA2G2CLPAR1LPAR3LPAR2PLA2G2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115504945-A | Ionizable heterocyclic lipid molecule and application thereof in preparation of lipid nanoparticles | 南京吉迈生物技术有限公司 | 2022-12-23 | — | — | CN | claimed |
| EP-3397244-B1 | TREATMENT OF BREAST CANCER USING A COMBINATION OF A CATIONIC LIPOSOMAL FORMULATION OF TAXANE, A NON-LIPOSOMAL FORMULATION OF TAXANE AND A FURTHER ACTIVE AGENT | SYNCORE BIOTECHNOLOGY CO LTD (TW) | 2021-10-06 | — | — | EP | claimed |
| CN-114787127-B | Ionizable lipids and nanoparticle compositions thereof | 世代生物公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117241780-A | Biological delivery system | 帕帝塞拉公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-116082184-B | Ionizable lipid and lipid nanoparticle based on cyclohexanediamine, and preparation method and application thereof | 山东大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-116082184-A | Ionizable lipid and lipid nanoparticle based on cyclohexanediamine, and preparation method and application thereof | 山东大学 | 2023-05-09 | — | — | CN | disclosed |
| CN-113908292-B | Target-mediated nucleic acid nano preparation and preparation method thereof | 南京吉迈生物技术有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-113908292-A | Target-mediated nucleic acid nano preparation and preparation method thereof | 南京吉迈生物技术有限公司 | 2022-01-11 | — | — | CN | disclosed |
| US-4687766-A | MIXTURE OF OXICAM DERIVATIVES WITH PHOSPHOLIPID | A. NATTERMAN & CIE, GMBH (DE) | 1987-08-18 | — | — | US | disclosed |