Methane

Methane

SCHEMBL1075331

C.N#Cc1cccn1CCC(NS(=O)(=O)c1cccc2[nH]ccc12)C(=O)N1CCCC(CCC(=O)O)C1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCR10 P46092 20/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1311291 0.99 CCR10 (0.79) CCR10
SCHEMBL1076654 0.95 CCR10 (0.77) CCR10
SCHEMBL1312239 0.92 CCR10 (0.81) CCR10
SCHEMBL1077803 0.92 CCR10 (0.78) CCR10
SCHEMBL1314404 0.92 CCR10 (0.82) CCR10
SCHEMBL1311174 0.91 CCR10 (0.83) CCR10
SCHEMBL1074392 0.90 CCR10 (0.76) CCR10
SCHEMBL1038254 0.88 CCR10 (0.86) CCR10
SCHEMBL12116833 0.88 CCR10 (0.80) CCR10
SCHEMBL1076768 0.88 CCR10 (0.80) CCR10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2276731-A1 2-SULFONYLAMINO-4-HETEROARYL BUTYRAMIDE ANTAGONISTS OF CCR10 Boehringer Ingelheim International GmbH (DE) 2011-01-26 EP disclosed
WO-2009126675-A1 2-SULFONYLAMINO-4-HETEROARYL BUTYRAMIDE ANTAGONISTS OF CCR10 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-10-15 WO disclosed