Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95279 | 0.82 | HDAC1 (0.46) | TAAR1CALM1TRPV1HDAC1HDAC3 | |
| SCHEMBL9335512 | 0.81 | TAAR1 (0.46) | TAAR1CALM1TRPV1HDAC1HDAC3 | |
| SCHEMBL9214607 | 0.81 | TAAR1 (0.62) | TAAR1CALM1TRPV1HDAC1HDAC3 | |
| SCHEMBL1174021 | 0.80 | CYP2D6 (0.47) | TAAR1MAOAMAOBCYP2D6NPC1 | |
| SCHEMBL5659188 | 0.80 | TAAR1 (0.52) | TAAR1CALM1MAOAMAOBCYP2D6 | |
| SCHEMBL5333274 | 0.78 | CHRM1 (0.42) | MAOAMAOBNPC1RAB9AKDM1A | |
| SCHEMBL14103267 | 0.77 | TAAR1 (0.49) | TAAR1CALM1MAOAMAOBCYP2D6 | |
| SCHEMBL20356528 | 0.77 | TAAR1 (0.73) | TAAR1CALM1MAOAMAOBCYP2D6 | |
| SCHEMBL29829182 | 0.77 | TAAR1 (0.73) | TAAR1CALM1MAOAMAOBCYP2D6 | |
| SCHEMBL3023636 | 0.77 | TAAR1 (0.49) | TAAR1CALM1MAOAMAOBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4684739-A | HYPOTENSIVE AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1987-08-04 | — | — | US | disclosed |
| EP-0054304-B1 | ALKYLENEDIOXYBENZENE DERIVATIVES, ACID ADDITION SALTS THEREOF AND A METHOD FOR THEIR PREPARATION | MITSUBISHI KASEI CORPORATION (JP) | 1984-08-15 | — | — | EP | disclosed |
| EP-0054304-A1 | Alkylenedioxybenzene derivatives, acid addition salts thereof and a method for their preparation | MITSUBISHI KASEI CORPORATION (JP) | 1982-06-23 | — | — | EP | disclosed |