SCHEMBL107538

SCHEMBL107538

O=C(O)c1cccnc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 3/20 0.67
KDM4E B2RXH2 5/20 0.65
TDP1 Q9NUW8 1/20 0.65
ALDH1A1 P00352 7/20 0.63
L3MBTL1 Q9Y468 2/20 0.63
ALOX15 P16050 2/20 0.63
CYP3A4 P08684 1/20 0.63
MAPT P10636 1/20 0.63
TSHR P16473 1/20 0.63
BLM P54132 1/20 0.63
AGER Q15109 1/20 0.63
NPSR1 Q6W5P4 1/20 0.63
SMN1; SMN2 Q16637 3/20 0.61
LMNA P02545 2/20 0.61
DHODH Q02127 2/20 0.52
KDM6B O15054 1/20 0.52
KDM6A O15550 1/20 0.52
TET3 O43151 1/20 0.52
KDM4A O75164 1/20 0.52
KDM4B O94953 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29514689 1.00 NAPRT (0.67) NAPRTKDM4ETDP1ALDH1A1L3MBTL1
Ammonia Solution, Strong SCHEMBL7970150 0.98 NAPRT (0.64) NAPRTKDM4ETDP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL2164505 0.98 NAPRT (0.64) NAPRTKDM4ETDP1ALDH1A1L3MBTL1
SCHEMBL10631520 0.98 NAPRT (0.64) NAPRTKDM4ETDP1ALDH1A1L3MBTL1
Ammonia Solution, Strong SCHEMBL7970154 0.98 NAPRT (0.64) NAPRTKDM4ETDP1ALDH1A1L3MBTL1
SCHEMBL7904344 0.98 NAPRT (0.64) NAPRTKDM4ETDP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL2164502 0.96 NAPRT (0.62) NAPRTKDM4ETDP1ALDH1A1L3MBTL1
Pyridine SCHEMBL28979292 0.90 NAPRT (0.56) NAPRTKDM4ETDP1ALDH1A1L3MBTL1
SCHEMBL27349912 0.86 NAPRT (0.51) NAPRTKDM4ETDP1ALDH1A1L3MBTL1
SCHEMBL7301605 0.80 KDM4E (0.47) NAPRTKDM4ETDP1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1781 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
WO-2025121958-A1 COMPOSITION FOR TREATING OR PREVENTING RECURRENCE OF CHONDROSARCOMA COMPRISING SIRT1 INHIBITOR 서울대학교산학협력단 2025-06-12 WO claimed
CN-119880877-A Online detection method and system for acetylation reaction conversion rate of aromatic hydroxy formic acid compound 浙江大学 2025-04-25 CN claimed
CN-119725552-A Flame-retardant composite current collector and preparation method thereof 艾姆西艾(宿迁)电池技术有限公司 2025-03-28 CN claimed
CN-119504571-A Right-embedded alcohol or fenchyl alcohol ester derivatives of 2-hydroxy nicotinic acid and pharmaceutical application thereof 苏州缘聚医药科技有限公司 2025-02-25 CN claimed
CN-119236874-A Sewage treatment agent and sewage treatment method 河北惠泽智能水处理科技有限公司 2025-01-03 CN claimed
US-12077680-B2 Polishing composition, production method of the same, polishing method and a manufacturing method of a semiconductor substrate FUJIMI INCORPORATED (JP) 2024-09-03 US claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-118206481-A Right-embedded alcohol or fenchyl alcohol ester derivatives of 2-hydroxy nicotinic acid and pharmaceutical application thereof 苏州南医大创新中心 2024-06-18 CN claimed
CN-114891029-B Cd (cadmium sulfide) 2+ Base coordination compound SUST-WJ-12, and preparation method and application thereof 陕西科技大学 2024-03-19 CN claimed
WO-1991016820-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1991-11-14 WO claimed
US-4994273-A Solubility modulated drug delivery device MERCK & CO., INC. (US) 1991-02-19 US claimed
US-4960896-A Halogenation with hypohalite salts A. H. ROBINS COMPANY, INC. (US) 1990-10-02 US claimed
US-4946686-A Solubility modulated drug delivery system MERCK & CO., INC. (US) 1990-08-07 US claimed
EP-0225172-A1 Process for the preparation of 5-chloro and 5-bromo-2-hydroxynicotinicacids A.H. ROBINS COMPANY, INCORPORATED (US) 1987-06-10 EP claimed
EP-0064378-B1 AFFINITY CHROMATOGRAPHY USING METAL IONS The Public Health Laboratory Service Board (GB) 1987-02-11 EP claimed
US-4431546-A SEPARATION OF BIOLOGICAL MATERIAL IN A SOLUTION CONTAINING A METAL SALT USING A MATRIX-DYE LIGAND THE PUBLIC HEALTH LABORATORY SERVICES BOARD (GB) 1984-02-14 US claimed
EP-0064378-A2 Affinity chromatography using metal ions The Public Health Laboratory Service Board (GB) 1982-11-10 EP claimed
US-4081451-A Process for preparing 2-halogeno nicotinic acids SCHERING CORPORATION (US) 1978-03-28 US claimed
US-3954533-A NITROCELLULOSE, NITROGLYCERIN AND BALLISTIC MODIFIERS OF LEAD- AND COPPER- SALTS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1976-05-04 US claimed