Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | IDE | P14735 | 1/20 | 0.34 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.34 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.34 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10754614 | 1.00 | KMT2A (0.40) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL9720539 | 0.91 | MEN1 (0.39) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL9720544 | 0.91 | MEN1 (0.39) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL6339982 | 0.88 | KMT2A (0.42) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL6339979 | 0.88 | KMT2A (0.42) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL17193050 | 0.88 | KMT2A (0.42) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL13225679 | 0.86 | MEN1 (0.39) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL10692113 | 0.84 | MAPT (0.41) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL2670497 | 0.84 | MEN1 (0.37) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL2670499 | 0.84 | MEN1 (0.37) | KMT2AMEN1NPSR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4684648-A | Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds and compositions thereof | OTSUKA PHARMACEUTICAL COMPANY LIMITED (JP) | 1987-08-04 | — | — | US | disclosed |
| EP-0181521-A1 | Antimicrobial 1-substituted Phenyl-4-oxoquinoline-3-carboxylic acid compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-21 | — | — | EP | disclosed |