Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.46 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.46 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29758064 | 0.84 | GRIK1 (0.56) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11077376 | 0.84 | GRIK1 (0.56) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL10022405 | 0.80 | GRIK1 (0.52) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL10759377 | 0.79 | IDO1 (0.49) | IDO1NOTUM | |
| SCHEMBL10759778 | 0.79 | IDO1 (0.56) | MEN1KMT2AIDO1MAPTLMNA | |
| SCHEMBL28850718 | 0.76 | GRIA1 (0.56) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL10786918 | 0.74 | GRIK1 (0.57) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL10758932 | 0.74 | NOTUM (0.74) | MEN1KMT2AIDO1MAPTLMNA | |
| SCHEMBL995544 | 0.73 | GRIK1 (0.56) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL1237406 | 0.73 | GRIA1 (0.56) | GRIK1GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4661603-A | ENZYME INHIBITORS; VASODILATORS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1987-04-28 | — | — | US | disclosed |
| EP-0110996-B1 | IMIDAZOLE DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-09-03 | — | — | EP | disclosed |
| US-4581369-A | THROMBANE INHIBITORS, ANTICOAGULANTS, VASODILATORS, AND TREATMENT OF LIVER DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1986-04-08 | — | — | US | disclosed |