Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | BLM | P54132 | 3/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | RECQL | P46063 | 5/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | THPO | P40225 | 2/20 | 0.57 |
| ▸ | APEX1 | P27695 | 2/20 | 0.57 |
| ▸ | MTOR | P42345 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19565601 | 1.00 | TDP1 (0.66) | TDP1LMNABLMADRA1ANR1I2 | |
| SCHEMBL19565603 | 1.00 | TDP1 (0.66) | TDP1LMNABLMADRA1ANR1I2 | |
| SCHEMBL10754856 | 1.00 | TDP1 (0.66) | TDP1LMNABLMADRA1ANR1I2 | |
| SCHEMBL19565602 | 1.00 | TDP1 (0.66) | TDP1LMNABLMADRA1ANR1I2 | |
| SCHEMBL19565604 | 1.00 | TDP1 (0.66) | TDP1LMNABLMADRA1ANR1I2 | |
| Hydrochloric Acid SCHEMBL10362778 | 0.98 | TDP1 (0.64) | TDP1LMNABLMADRA1ANR1I2 | |
| Oxalic Acid SCHEMBL10757594 | 0.95 | TDP1 (0.65) | TDP1LMNABLMADRA1ANR1I2 | |
| SCHEMBL10362671 | 0.86 | TDP1 (0.64) | TDP1LMNABLMADRA1ANR1I2 | |
| SCHEMBL19565609 | 0.84 | TDP1 (0.62) | TDP1LMNABLMADRA1ANR1I2 | |
| SCHEMBL19565608 | 0.84 | TDP1 (0.62) | TDP1LMNABLMADRA1ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170319694-A1 | DIHYDROXYPHENYL NEUROTRANSMITTER COMPOUNDS, COMPOSITIONS AND METHODS | AUSPEX PHARMACEUTICALS INC (US) | 2017-11-09 | — | — | US | disclosed |
| EP-0218440-A2 | N-Methylphenylserine alkyl ester derivatives and uses thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1987-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170319694-A1 | DIHYDROXYPHENYL NEUROTRANSMITTER COMPOUNDS, COMPOSITIONS AND METHODS | SLC18A2, COMT, SLC6A2 | TDP1 1161/4885LMNA 3543/4885BLM 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.