Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19024566 | 1.00 | ACE (0.57) | ACEACE2L3MBTL1RENGNAI3 | |
| SCHEMBL5035980 | 1.00 | ACE (0.57) | ACEACE2L3MBTL1RENGNAI3 | |
| SCHEMBL19024592 | 1.00 | ACE (0.57) | ACEACE2L3MBTL1RENGNAI3 | |
| SCHEMBL10537390 | 1.00 | ACE (0.57) | ACEACE2L3MBTL1RENGNAI3 | |
| SCHEMBL9362232 | 1.00 | ACE (0.57) | ACEACE2L3MBTL1RENGNAI3 | |
| SCHEMBL10406629 | 1.00 | ACE (0.57) | ACEACE2L3MBTL1RENGNAI3 | |
| SCHEMBL15650373 | 1.00 | ACE (0.57) | ACEACE2L3MBTL1RENGNAI3 | |
| SCHEMBL5035740 | 1.00 | ACE (0.57) | ACEACE2L3MBTL1RENGNAI3 | |
| SCHEMBL21853572 | 1.00 | ACE (0.57) | ACEACE2L3MBTL1RENGNAI3 | |
| SCHEMBL5035738 | 1.00 | ACE (0.57) | ACEACE2L3MBTL1RENGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240554-A1 | TRANSDERMAL AND SYSTEMIC PREPARATION AND METHOD | RAJADHYAKSHA, Vithal J. (US) | 1987-10-14 | — | — | EP | disclosed |
| WO-1987001935-A1 | TRANSDERMAL AND SYSTEMIC PREPARATION AND METHOD | RAJADHYAKSHA VITHAL J | 1987-04-09 | — | — | WO | disclosed |