Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14595668 | 0.83 | CHRM4 (0.33) | CHRM4NPC1RAB9AHPGDSNAMPT | |
| SCHEMBL8368741 | 0.83 | CHRM4 (0.39) | CHRM4NPC1RAB9AHPGDSNAMPT | |
| SCHEMBL10757360 | 0.80 | CHRM4 (0.33) | CHRM4NPC1RAB9AHPGDSNAMPT | |
| SCHEMBL10854456 | 0.73 | NAMPT (0.35) | CHRM4NPC1RAB9AHPGDSNAMPT | |
| SCHEMBL12331137 | 0.71 | — | — | |
| SCHEMBL4099547 | 0.71 | KAT2B (0.33) | CHRM4BRD4 | |
| SCHEMBL12409239 | 0.71 | — | — | |
| SCHEMBL12332204 | 0.71 | — | — | |
| SCHEMBL12800866 | 0.71 | EPHX1 (0.43) | NPC1RAB9ABRD4CXCR2 | |
| SCHEMBL10756543 | 0.71 | RECQL (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707478-A | ANTIPROTOZOA AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |