SCHEMBL10757384

SCHEMBL10757384

C=CCC1(CC=C)CC(C(=O)C2CC(CC=C)(CC=C)NC(CC=C)(CC=C)C2)CC(CC=C)(CC=C)N1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10816640 0.86 CYP2C19 (0.43) KMT2A
SCHEMBL2246628 0.76
SCHEMBL10757390 0.72
SCHEMBL10357731 0.71
SCHEMBL30046 0.71
SCHEMBL11586996 0.71 GAA (0.35) KMT2A
SCHEMBL9039925 0.70 GAA (0.37)
SCHEMBL9815859 0.69
SCHEMBL6425230 0.69
SCHEMBL9300043 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4173599-A 2,2,6,6-Tetraalkyl-4-piperidyl ketones and ketals as stabilizers for synthetic polymers ARGUS CHEMICAL CORPORATION (US) 1979-11-06 US claimed
EP-0042622-B1 Spiro[2,2,6,6-tetramethyl-piperidine-4,2'-(1',3'-dioxo(ol)an]-derivatives and stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1987-08-19 EP disclosed
EP-0045358-B1 2,2,6,6-TETRAMETHYL-4-PIPERIDYL SPIRO ALIPHATIC ETHERS AS STABILIZERS FOR SYNTHETIC POLYMERS ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1985-08-14 EP disclosed
US-4405736-A 2,2,6,6-Tetramethyl-4-piperidyl spiro aliphatic ethers and stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-09-20 US disclosed
US-4351915-A OXIDATION AND HEAT RESISTANCE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1982-09-28 US disclosed
EP-0045358-A2 2,2,6,6-Tetramethyl-4-piperidyl spiro aliphatic ethers as stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1982-02-10 EP disclosed
EP-0042622-A1 Spiro[2,2,6,6-tetramethyl-piperidine-4,2'-(1',3'-dioxo(ol)an]-derivatives and stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1981-12-30 EP disclosed
US-4173599-A 2,2,6,6-Tetraalkyl-4-piperidyl ketones and ketals as stabilizers for synthetic polymers ARGUS CHEMICAL CORPORATION (US) 1979-11-06 US disclosed
US-4173599-A 2,2,6,6-Tetraalkyl-4-piperidyl ketones and ketals as stabilizers for synthetic polymers ARGUS CHEMICAL CORPORATION (US) 1979-11-06 US disclosed
US-4173599-A 2,2,6,6-Tetraalkyl-4-piperidyl ketones and ketals as stabilizers for synthetic polymers ARGUS CHEMICAL CORPORATION (US) 1979-11-06 US disclosed