Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.47 |
| ▸ | CYP3A5 | P20815 | 7/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10758681 | 0.93 | CYP19A1 (0.52) | CYP19A1CYP3A4CYP3A5KCNA5 | |
| SCHEMBL10685895 | 0.81 | CYP19A1 (0.49) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL836951 | 0.80 | CYP19A1 (0.48) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL10730981 | 0.80 | CYP19A1 (0.48) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL10732564 | 0.79 | CYP19A1 (0.47) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL10683122 | 0.78 | CYP19A1 (0.46) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL10727604 | 0.78 | CYP19A1 (0.46) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL10734542 | 0.77 | CYP19A1 (0.43) | CYP19A1CYP3A4CYP3A5 | |
| Ethylene SCHEMBL10733781 | 0.77 | CYP19A1 (0.46) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL10734528 | 0.77 | CYP3A4 (0.46) | CYP19A1CYP3A4CYP3A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4678790-A | AGRICULTURE HORTICULTURE | HOFFMAN-LA ROCHE INC. (US) | 1987-07-07 | — | — | US | disclosed |