SCHEMBL10758671

SCHEMBL10758671

CC#CCCC(C)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 2/20 0.48
CYP1A2 P05177 1/20 0.48
BLM P54132 1/20 0.42
ACE2 Q9BYF1 1/20 0.39
LTA4H P09960 1/20 0.38
GRIK1 P39086 1/20 0.37
GRIK2 Q13002 1/20 0.37
FOLH1 Q04609 2/20 0.33
NAALAD2 Q9Y3Q0 2/20 0.33
ENPEP Q07075 2/20 0.33
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4970051 0.88 GABRR1 (0.54) GABRR1CYP1A2BLMACE2LTA4H
SCHEMBL8681235 0.81 GRIK1 (0.39) GABRR1CYP1A2GRIK1GRIK2ENPEP
SCHEMBL5139179 0.77 GABRR1 (0.72) GABRR1CYP1A2BLMACE2LTA4H
SCHEMBL11740110 0.77 CYP1A2 (0.48) GABRR1CYP1A2BLMACE2LTA4H
SCHEMBL14214372 0.76
SCHEMBL576851 0.76
SCHEMBL7172784 0.76
SCHEMBL4289130 0.76
SCHEMBL15549648 0.76
SCHEMBL23139451 0.76 GRIK1 (0.53) CYP1A2BLMGRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014070092-A1 FUNCTIONALIZED CELLULOSE NANOCRYSTALS, A METHOD FOR THE PREPARATION THEREOF AND USE OF FUNCTIONALIZED CELLULOSE NANOCRYSTALS IN COMPOSITES AND FOR GRAFTING SWETREE TECHNOLOGIES AB (SE) 2014-05-08 WO disclosed
US-4708963-A Novel carbacyclins, their preparation and use SCHERING AKTIENGESELLSCHAFT (DE) 1987-11-24 US disclosed
US-4423067-A Carbacyclins, their preparation and use SCHERING AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed