Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.52 |
| ▸ | MGAM | O43451 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | SI | P14410 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307547 | 0.86 | HDAC3 (0.67) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL6982959 | 0.85 | HTR2A (0.62) | HTR2AHTR2CHTR2BHDAC3HDAC1 | |
| SCHEMBL29611986 | 0.85 | HTR2A (0.62) | HTR2AHTR2CHTR2BHDAC3HDAC1 | |
| SCHEMBL3656418 | 0.85 | HTR2A (0.62) | HTR2AHTR2CHTR2BHDAC3HDAC1 | |
| SCHEMBL6986747 | 0.85 | HTR2A (0.62) | HTR2AHTR2CHTR2BHDAC3HDAC1 | |
| SCHEMBL29272526 | 0.84 | HTR2A (0.60) | HTR2AHTR2CHTR2BHDAC3HDAC1 | |
| SCHEMBL29272546 | 0.84 | HTR2A (0.60) | HTR2AHTR2CHTR2BHDAC3HDAC1 | |
| SCHEMBL27975035 | 0.84 | HTR2A (0.60) | HTR2AHTR2CHTR2BHDAC3HDAC1 | |
| SCHEMBL29272698 | 0.84 | HTR2A (0.60) | HTR2AHTR2CHTR2BHDAC3HDAC1 | |
| Ammonia Solution, Strong SCHEMBL11124638 | 0.84 | HTR2A (0.60) | HTR2AHTR2CHTR2BHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103347874-A | Dimeric iap inhibitors | NOVARTIS AG | 2013-10-09 | — | — | CN | disclosed |
| EP-0090312-B1 | 3-ACYL SUBSTITUTED DERIVATIVES OF 2- OR 4-THIAZOLIDINE-CARBOXYLIC ACID HAVING A PHYTO GROWTH REGULATING AND BIOSTIMULATING ACTION | Montedison S.p.A. (IT) | 1987-09-09 | — | — | EP | disclosed |
| US-4685954-A | 3-acyl substituted of 2- or 4-thiazolidine-carboxylic acid having a phyto growth regulating and biostimulating action | MONTEDISON S.P.A (IT) | 1987-08-11 | — | — | US | disclosed |
| US-4655818-A | 3-acyl substituted derivatives of 2- or 4-thiazolidine-carboxylic acid having a phyto growth regulating and biostimulating action | MONTEDISON S.P.A. (IT) | 1987-04-07 | — | — | US | disclosed |
| EP-0090312-A2 | 3-Acyl substituted derivatives of 2- or 4-thiazolidine-carboxylic acid having a phyto growth regulating and biostimulating action | Montedison S.p.A. (IT) | 1983-10-05 | — | — | EP | disclosed |