Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 13/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.43 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10766074 | 0.88 | PDE3A (0.40) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10762398 | 0.87 | PDE3A (0.39) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10761353 | 0.85 | PDE3A (0.39) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10760774 | 0.85 | PDE3A (0.41) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10763339 | 0.82 | PDE3A (0.43) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10759456 | 0.82 | PDE3A (0.45) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10763665 | 0.81 | PDE3A (0.44) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10763324 | 0.81 | PDE3A (0.42) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10764750 | 0.81 | PDE3B (0.41) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10761226 | 0.81 | PDE3A (0.49) | PDE3APDE4BPDE3BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |