Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 6/20 | 0.65 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.65 |
| ▸ | PDE2A | O00408 | 2/20 | 0.65 |
| ▸ | PDE1A | P54750 | 2/20 | 0.65 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.65 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.65 |
| ▸ | PDE4A | P27815 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | PDE5A | O76074 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10762355 | 0.99 | PDE3A (0.64) | PDE3APDE3BPDE2APDE1APDE1B | |
| SCHEMBL10365674 | 0.85 | PDE3B (0.45) | PDE3APDE3BPDE2APDE1APDE1B | |
| Hydrochloric Acid SCHEMBL10367895 | 0.84 | PDE3B (0.44) | PDE3APDE3BPDE2APDE1APDE1B | |
| SCHEMBL10364610 | 0.83 | PDE3B (0.49) | PDE3APDE3BPDE2APDE1APDE1B | |
| SCHEMBL10365327 | 0.80 | PDE2A (0.41) | PDE3APDE3BPDE2APDE1APDE1B | |
| SCHEMBL10758959 | 0.80 | PDE3A (0.68) | PDE3APDE3BPDE2APDE1APDE1B | |
| Hydrochloric Acid SCHEMBL10760519 | 0.80 | PDE3A (0.67) | PDE3APDE3BPDE2APDE1APDE1B | |
| SCHEMBL10763661 | 0.80 | PDE3B (0.41) | PDE3APDE3BPDE2APDE1APDE1B | |
| SCHEMBL7411067 | 0.79 | PDE3A (1.00) | PDE3APDE3BPDE2APDE1APDE1B | |
| SCHEMBL10365328 | 0.78 | PDE2A (0.39) | PDE3APDE3BPDE2APDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699914-A | CONGESTIVE HEART FAILURE | A. NATTERMANN & CIE GMBH (DE) | 1987-10-13 | — | — | US | disclosed |