Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.50 |
| ▸ | PDE2A | O00408 | 3/20 | 0.50 |
| ▸ | PDE1A | P54750 | 2/20 | 0.50 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.50 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.50 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10760519 | 0.81 | PDE3A (0.67) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL10758959 | 0.80 | PDE3A (0.68) | PDE3BPDE3APDE2APDE1APDE1B | |
| Hydrochloric Acid SCHEMBL10764650 | 0.79 | PDE3B (0.43) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL10364553 | 0.78 | PDE3B (0.44) | PDE3BPDE3APDE2APDE1APDE1B | |
| Hydrochloric Acid SCHEMBL10366384 | 0.77 | PDE3B (0.47) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL10365557 | 0.75 | PDE3B (0.47) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL10758369 | 0.73 | PDE3B (0.49) | PDE3BPDE3APDE2APDE1APDE1B | |
| Hydrochloric Acid SCHEMBL10763679 | 0.72 | PDE2A (0.43) | PDE3BPDE3APDE2APDE1APDE1B | |
| Hydrochloric Acid SCHEMBL10364633 | 0.72 | PDE3B (0.44) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL10365669 | 0.71 | PDE2A (0.43) | PDE3BPDE3APDE2APDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699914-A | CONGESTIVE HEART FAILURE | A. NATTERMANN & CIE GMBH (DE) | 1987-10-13 | — | — | US | disclosed |