Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.68 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 4/20 | 0.56 |
| ▸ | HTR7 | P34969 | 4/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ILK | Q13418 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088124 | 0.95 | UBE2T (0.66) | UBE2TASIC3SMN1; SMN2ALOX15HTT | |
| SCHEMBL4703105 | 0.93 | UBE2T (0.64) | UBE2TASIC3SMN1; SMN2ALOX15HTT | |
| SCHEMBL29111661 | 0.93 | UBE2T (0.64) | UBE2TASIC3SMN1; SMN2ALOX15HTT | |
| SCHEMBL11437569 | 0.93 | UBE2T (0.64) | UBE2TASIC3SMN1; SMN2ALOX15HTT | |
| SCHEMBL4700806 | 0.93 | UBE2T (0.64) | UBE2TASIC3SMN1; SMN2ALOX15HTT | |
| SCHEMBL3529770 | 0.89 | UBE2T (0.72) | UBE2TASIC3SMN1; SMN2ALOX15HTT | |
| SCHEMBL9641726 | 0.89 | SMN1; SMN2 (0.70) | UBE2TASIC3SMN1; SMN2ALOX15HTT | |
| Hydrochloric Acid SCHEMBL12477869 | 0.87 | UBE2T (0.70) | UBE2TASIC3SMN1; SMN2ALOX15HTT | |
| Bromide SCHEMBL11522514 | 0.85 | SMN1; SMN2 (0.66) | UBE2TASIC3SMN1; SMN2ALOX15HTT | |
| SCHEMBL19372016 | 0.85 | UBE2T (0.70) | UBE2TASIC3SMN1; SMN2ALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4026815-A | ADDING A PHOSPHONOCARBOXYLIC ACID AND A BENZIMIDAZOLE DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | claimed |
| US-4000079-A | ANTIFREEZE ADDITIVES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | claimed |
| CN-113024483-A | Preparation method of 2-substituted benzothiazole derivative | 无锡鸣鹭医药科技有限公司 | 2021-06-25 | — | — | CN | disclosed |
| EP-0226016-A1 | Process for inhibiting hydrogen-induced corrosion of metallic materials | BAYER AG (DE) | 1987-06-24 | — | — | EP | disclosed |
| EP-0163458-A1 | Tetrahydronaphthalenols for the treatment of hypertension | E.R. Squibb & Sons, Inc. (US) | 1985-12-04 | — | — | EP | disclosed |
| US-4235838-A | IN OIL AND GAS WELLS | PETROLITE CORPORATION (US) | 1980-11-25 | — | — | US | disclosed |
| US-4026815-A | ADDING A PHOSPHONOCARBOXYLIC ACID AND A BENZIMIDAZOLE DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |
| US-4000079-A | ANTIFREEZE ADDITIVES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |