Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 8/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.53 |
| ▸ | PDE2A | O00408 | 3/20 | 0.53 |
| ▸ | PDE1A | P54750 | 1/20 | 0.53 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.53 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.53 |
| ▸ | ADH5 | P11766 | 6/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10763411 | 0.93 | PDE3B (0.51) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL10756489 | 0.91 | PDE3B (0.55) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL10762139 | 0.83 | PDE3B (0.72) | PDE3BPDE3APDE2APDE1APDE1B | |
| Hydrochloric Acid SCHEMBL10761419 | 0.82 | PDE3B (0.71) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL10365667 | 0.81 | PDE4A (0.38) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL10363632 | 0.80 | PDE3B (0.38) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL10363624 | 0.75 | PDE4A (0.37) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL10365547 | 0.74 | PDE4A (0.36) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL11118932 | 0.73 | PDE3B (0.57) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10363623 | 0.72 | PDE4A (0.44) | PDE3BPDE3APDE2APDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699914-A | CONGESTIVE HEART FAILURE | A. NATTERMANN & CIE GMBH (DE) | 1987-10-13 | — | — | US | disclosed |