Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10763600 | 1.00 | PTGS1 (0.61) | PTGS1PTGS2NPC1RAB9ALMNA | |
| SCHEMBL10763055 | 0.84 | PTGS1 (0.62) | PTGS1PTGS2NPC1RAB9ALMNA | |
| SCHEMBL10763057 | 0.84 | PTGS1 (0.62) | PTGS1PTGS2NPC1RAB9ALMNA | |
| SCHEMBL10762889 | 0.80 | PTGS1 (0.72) | PTGS1PTGS2NPC1RAB9ALMNA | |
| SCHEMBL10764623 | 0.80 | PTGS1 (0.61) | PTGS1PTGS2NPC1RAB9ALMNA | |
| SCHEMBL10762887 | 0.80 | PTGS1 (0.72) | PTGS1PTGS2NPC1RAB9ALMNA | |
| SCHEMBL10764621 | 0.80 | PTGS1 (0.61) | PTGS1PTGS2NPC1RAB9ALMNA | |
| SCHEMBL10765189 | 0.80 | PTGS1 (0.38) | PTGS1PTGS2LMNAKDM4ECYP1A2 | |
| SCHEMBL10765187 | 0.80 | PTGS1 (0.38) | PTGS1PTGS2LMNAKDM4ECYP1A2 | |
| SCHEMBL10764751 | 0.79 | PTGS1 (0.60) | PTGS1PTGS2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |