Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.57 |
| ▸ | CMA1 | P23946 | 6/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 3/20 | 0.50 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764016 | 0.90 | CMA1 (0.54) | ACECMA1 | |
| SCHEMBL15231898 | 0.89 | SLC6A2 (0.59) | ACECMA1SLC6A2XIAPDPP3 | |
| SCHEMBL15231343 | 0.89 | SLC6A2 (0.59) | ACECMA1SLC6A2XIAPDPP3 | |
| SCHEMBL15231906 | 0.89 | SLC6A2 (0.59) | ACECMA1SLC6A2XIAPDPP3 | |
| SCHEMBL10766006 | 0.89 | ACE (0.57) | ACECMA1SLC6A2XIAPDPP3 | |
| SCHEMBL10768815 | 0.88 | ACE (0.59) | ACE | |
| SCHEMBL10768813 | 0.88 | ACE (0.59) | ACE | |
| SCHEMBL30271249 | 0.86 | SLC6A2 (0.60) | ACECMA1SLC6A2DPP3OPRM1 | |
| SCHEMBL29637436 | 0.86 | SLC6A2 (0.60) | ACECMA1SLC6A2OPRM1OPRD1 | |
| SCHEMBL1289940 | 0.85 | CMA1 (0.54) | ACECMA1SLC6A2XIAPDPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230922-A2 | Use of peptides in the preparation of agents for the treatment of coronary diseases or organic brain syndrome | BOEHRINGER INGELHEIM KG (DE) | 1987-08-05 | — | — | EP | disclosed |
| EP-0174571-A2 | Derivatives of amino acids, process for their preparation and pharmaceutical compositions | BOEHRINGER INGELHEIM KG (DE) | 1986-03-19 | — | — | EP | disclosed |