Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10091159 | 1.00 | ESR2 (0.55) | ESR2SLC18A3SIGMAR1GRIN2BDRD2 | |
| SCHEMBL10765237 | 1.00 | ESR2 (0.55) | ESR2SLC18A3SIGMAR1GRIN2BDRD2 | |
| SCHEMBL594418 | 0.93 | ESR2 (0.61) | ESR2SLC18A3SIGMAR1GRIN2BDRD2 | |
| Formic Acid SCHEMBL18406242 | 0.89 | ESR2 (0.50) | ESR2SLC18A3SIGMAR1GRIN2BDRD2 | |
| SCHEMBL10091208 | 0.88 | NPC1 (0.54) | ESR2SLC18A3SIGMAR1 | |
| SCHEMBL19207133 | 0.85 | ESR2 (0.53) | ESR2SLC18A3SIGMAR1DRD2CYP2D6 | |
| SCHEMBL8961557 | 0.83 | ESR2 (0.47) | ESR2SLC18A3SIGMAR1GRIN2BDRD2 | |
| SCHEMBL11029181 | 0.82 | AKR1C3 (0.46) | ESR2SLC18A3SIGMAR1GRIN2BCYP2D6 | |
| SCHEMBL6456032 | 0.82 | AKR1C3 (0.46) | ESR2SLC18A3SIGMAR1GRIN2BCYP2D6 | |
| SCHEMBL10091181 | 0.82 | ESR2 (0.50) | ESR2SLC18A3SIGMAR1GRIN2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094487-B1 | HYDROTERPHENYLS, THEIR PREPARATION AND THEIR USE IN DIELECTRIC LIQUID CRYSTAL MATERIAL | MERCK PATENT GmbH (DE) | 1987-09-09 | — | — | EP | disclosed |
| US-4620938-A | Hydroterphenyls | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-11-04 | — | — | US | disclosed |
| EP-0094487-A1 | Hydroterphenyls, their preparation and their use in dielectric liquid crystal material | MERCK PATENT GmbH (DE) | 1983-11-23 | — | — | EP | disclosed |