Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 8/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10765487 | 0.86 | PDE3B (0.41) | PDE3BPDE3APBRM1BRD4CREBBP | |
| SCHEMBL10760260 | 0.84 | PDE3B (0.42) | PDE3BPDE3APBRM1BRD4CREBBP | |
| SCHEMBL10761795 | 0.83 | PDE3B (0.43) | PDE3BPDE3APBRM1BRD4CREBBP | |
| SCHEMBL10765960 | 0.82 | PDE3B (0.43) | PDE3BPDE3APBRM1BRD4CREBBP | |
| SCHEMBL10769782 | 0.81 | PDE3A (0.37) | PDE3BPDE3A | |
| SCHEMBL10769626 | 0.80 | PDE3A (0.44) | PDE3BPDE3A | |
| SCHEMBL10762825 | 0.80 | PDE3A (0.42) | PDE3BPDE3A | |
| SCHEMBL10762787 | 0.80 | PDE3A (0.42) | PDE3BPDE3A | |
| SCHEMBL10765566 | 0.80 | PDE3A (0.44) | PDE3BPDE3A | |
| SCHEMBL10760714 | 0.79 | PDE3A (0.42) | PDE3BPDE3APBRM1BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |