Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5654346 | 0.91 | ACE (0.56) | ACEACE2MAPTREN | |
| SCHEMBL5035700 | 0.91 | ACE (0.53) | ACEACE2MEN1KMT2A | |
| SCHEMBL10537401 | 0.91 | ACE (0.53) | ACEACE2MEN1KMT2A | |
| SCHEMBL5035966 | 0.91 | ACE (0.53) | ACEACE2MEN1KMT2A | |
| SCHEMBL5035703 | 0.91 | ACE (0.53) | ACEACE2MEN1KMT2A | |
| SCHEMBL5040361 | 0.91 | ACE (0.53) | ACEACE2MEN1KMT2A | |
| SCHEMBL10537420 | 0.91 | ACE (0.53) | ACEACE2MEN1KMT2A | |
| SCHEMBL9222332 | 0.91 | ACE (0.53) | ACEACE2MEN1KMT2A | |
| SCHEMBL5042595 | 0.91 | ACE (0.53) | ACEACE2MEN1KMT2A | |
| SCHEMBL5040468 | 0.91 | ACE (0.53) | ACEACE2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240554-A1 | TRANSDERMAL AND SYSTEMIC PREPARATION AND METHOD | RAJADHYAKSHA, Vithal J. (US) | 1987-10-14 | — | — | EP | disclosed |
| WO-1987001935-A1 | TRANSDERMAL AND SYSTEMIC PREPARATION AND METHOD | RAJADHYAKSHA VITHAL J | 1987-04-09 | — | — | WO | disclosed |