Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 9/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10768383 | 0.87 | PDE3A (0.42) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10763253 | 0.87 | PDE3A (0.42) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10764734 | 0.87 | PDE3A (0.45) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10765935 | 0.83 | PDE3A (0.39) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10760785 | 0.82 | PDE3A (0.38) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10764057 | 0.81 | PDE3A (0.41) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10764697 | 0.80 | PDE3B (0.45) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10767001 | 0.80 | PDE3A (0.41) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10767048 | 0.80 | PDE3A (0.39) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL10765837 | 0.80 | PDE3A (0.39) | PDE3APDE4BPDE3BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |