Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.43 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10769548 | 1.00 | MEN1 (0.44) | MEN1KMT2ANPSR1DHODHGAA | |
| SCHEMBL19728768 | 0.92 | MEN1 (0.42) | MEN1KMT2ANPSR1DHODHGAA | |
| SCHEMBL20912617 | 0.90 | MEN1 (0.41) | MEN1KMT2ANPSR1DHODHGAA | |
| SCHEMBL19728766 | 0.90 | MEN1 (0.41) | MEN1KMT2ANPSR1DHODHGAA | |
| SCHEMBL9136542 | 0.88 | MEN1 (0.44) | MEN1KMT2ANPSR1DHODHGAA | |
| SCHEMBL9136537 | 0.88 | MEN1 (0.44) | MEN1KMT2ANPSR1DHODHGAA | |
| SCHEMBL8802943 | 0.88 | MEN1 (0.44) | MEN1KMT2ANPSR1DHODHGAA | |
| SCHEMBL9181641 | 0.88 | MEN1 (0.44) | MEN1KMT2ANPSR1DHODHGAA | |
| SCHEMBL5258617 | 0.87 | MEN1 (0.46) | MEN1KMT2ANPSR1DHODHGAA | |
| SCHEMBL5258612 | 0.87 | MEN1 (0.46) | MEN1KMT2ANPSR1DHODHGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235762-A1 | 8-Position substituted quinolone-carboxylic acid derivatives and process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |