Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.38 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25846831 | 0.79 | TSHR (0.64) | TP53TSHRNPC1RAB9AKMT2A | |
| SCHEMBL7239333 | 0.74 | TP53 (0.45) | TP53TSHRL3MBTL1NPC1RAB9A | |
| SCHEMBL6290520 | 0.74 | TP53 (0.45) | TP53TSHRL3MBTL1NPC1RAB9A | |
| SCHEMBL28967378 | 0.73 | TSHR (0.56) | TP53TSHRNPC1RAB9AKMT2A | |
| SCHEMBL8207998 | 0.73 | TSHR (0.72) | TP53TSHRNPC1RAB9AKMT2A | |
| SCHEMBL30137644 | 0.73 | TSHR (0.56) | TP53TSHRNPC1RAB9AKMT2A | |
| SCHEMBL14386718 | 0.73 | TSHR (0.72) | TP53TSHRNPC1RAB9AKMT2A | |
| SCHEMBL11542835 | 0.73 | TSHR (0.72) | TP53TSHRNPC1RAB9AKMT2A | |
| SCHEMBL10757354 | 0.73 | TSHR (0.72) | TP53TSHRNPC1RAB9AKMT2A | |
| SCHEMBL5663493 | 0.71 | TSHR (0.53) | TP53TSHRNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |