Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.83 |
| ▸ | ADRB3 | P13945 | 15/20 | 0.73 |
| ▸ | ADRB2 | P07550 | 13/20 | 0.73 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.69 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.69 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.63 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10772479 | 1.00 | SLC2A1 (0.83) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL9468413 | 0.97 | SLC2A1 (0.80) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL10433615 | 0.96 | SLC2A1 (0.78) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL11314022 | 0.94 | SLC2A1 (0.81) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL11182206 | 0.92 | SLC2A1 (0.83) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL10775119 | 0.92 | SLC2A1 (0.97) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL11314994 | 0.91 | SLC2A1 (0.78) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL10895539 | 0.91 | SLC2A1 (0.81) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL7153428 | 0.91 | SLC2A1 (0.81) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL7153891 | 0.91 | SLC2A1 (0.81) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233686-A2 | Bis phenyl ethanol amines and bis phenyoxypropanolamines having a beta-agonist activity | BEECHAM GROUP PLC (GB) | 1987-08-26 | — | — | EP | claimed |