Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 4/20 | 0.92 |
| ▸ | ADRB3 | P13945 | 14/20 | 0.89 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.89 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.89 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.77 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.77 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.77 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | GLA | P06280 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10772571 | 0.98 | SLC2A1 (0.96) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL10771766 | 0.97 | SLC2A1 (0.98) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL10772477 | 0.97 | SLC2A1 (0.98) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL10772478 | 0.97 | SLC2A1 (0.98) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL10771731 | 0.97 | SLC2A1 (0.98) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL10772591 | 0.97 | SLC2A1 (0.98) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL10772496 | 0.97 | SLC2A1 (0.98) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL10934792 | 0.94 | ADRB3 (1.00) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL7153657 | 0.94 | ADRB3 (1.00) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL7153660 | 0.94 | ADRB3 (1.00) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233686-A2 | Bis phenyl ethanol amines and bis phenyoxypropanolamines having a beta-agonist activity | BEECHAM GROUP PLC (GB) | 1987-08-26 | — | — | EP | claimed |
| EP-0233686-A2 | Bis phenyl ethanol amines and bis phenyoxypropanolamines having a beta-agonist activity | BEECHAM GROUP PLC (GB) | 1987-08-26 | — | — | EP | disclosed |