Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10777687 | 0.92 | TDP1 (0.61) | TDP1LMNASMN1; SMN2POLBMEN1 | |
| SCHEMBL10775978 | 0.87 | TDP1 (0.55) | TDP1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10775570 | 0.86 | TDP1 (0.59) | TDP1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10775113 | 0.85 | TDP1 (0.54) | TDP1LMNASMN1; SMN2POLBMEN1 | |
| SCHEMBL10772093 | 0.85 | TDP1 (0.56) | TDP1LMNASMN1; SMN2POLBMEN1 | |
| SCHEMBL10775512 | 0.85 | TDP1 (0.48) | TDP1LMNASMN1; SMN2POLBMEN1 | |
| SCHEMBL10777772 | 0.84 | TDP1 (0.50) | TDP1SMN1; SMN2MEN1KMT2ATTR | |
| SCHEMBL10785622 | 0.84 | TDP1 (0.81) | TDP1LMNASMN1; SMN2POLBMEN1 | |
| SCHEMBL10772927 | 0.83 | TDP1 (0.58) | TDP1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10775585 | 0.83 | TDP1 (0.58) | TDP1LMNASMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4690708-A | Herbicides derived from aryloxybenzenecarboxylic acid imides | RHONE-POULENC AGROCHIMIE (FR) | 1987-09-01 | — | — | US | disclosed |