Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10779759 | 0.86 | MAPT (0.67) | MAPTALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL9817053 | 0.82 | MAPT (0.74) | MAPTALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL5697776 | 0.80 | MAPT (1.00) | MAPTALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL11321295 | 0.80 | NT5E (0.63) | MAPTALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL10414562 | 0.80 | NT5E (0.47) | MAPTALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL10531279 | 0.80 | MAPT (0.53) | MAPTALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL3240949 | 0.80 | MAPT (0.66) | MAPTALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL9102010 | 0.79 | MAPT (0.71) | MAPTALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL30414503 | 0.79 | MAPT (0.71) | MAPTALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL10413180 | 0.79 | MAPT (0.52) | MAPTALDH1A1TDP1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151369-B1 | ASYMMETRICAL 1:2 CHROME COMPLEXES CONTAINING AN AZO COMPOUND AND AN AZOMETHINE COMPOUND | CIBA-GEIGY AG (CH) | 1987-09-09 | — | — | EP | disclosed |
| EP-0151369-A2 | Asymmetrical 1:2 chrome complexes containing an azo compound and an azomethine compound | CIBA-GEIGY AG (CH) | 1985-08-14 | — | — | EP | disclosed |
| EP-0018939-B1 | 1:2 METAL COMPLEX DYESTUFFS OF AZOMETHINES, PROCESS FOR THEIR PREPARATION AND PROCESS FOR DYEING AND PRINTING BY USING THESE DYESTUFFS | CIBA-GEIGY AG (CH) | 1983-10-05 | — | — | EP | disclosed |
| US-4315854-A | Chromium and cobalt complex amino hydroxy azomethine dyes | CIBA-GEIGY CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |
| EP-0018939-A1 | 1:2 Metal complex dyestuffs of azomethines, process for their preparation and process for dyeing and printing by using these dyestuffs | CIBA-GEIGY AG (CH) | 1980-11-12 | — | — | EP | disclosed |