Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | FASN | P49327 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9556288 | 1.00 | CYP11B1 (0.39) | CYP11B1CYP11B2ARTRPV4KDM1A | |
| SCHEMBL10432475 | 1.00 | CYP11B1 (0.39) | CYP11B1CYP11B2ARTRPV4KDM1A | |
| SCHEMBL9556397 | 1.00 | CYP11B1 (0.39) | CYP11B1CYP11B2ARTRPV4KDM1A | |
| SCHEMBL9556008 | 0.93 | CYP11B1 (0.38) | CYP11B1CYP11B2ARTRPV4KDM1A | |
| SCHEMBL10432816 | 0.93 | CYP11B1 (0.38) | CYP11B1CYP11B2ARTRPV4KDM1A | |
| SCHEMBL10781507 | 0.93 | CYP11B1 (0.38) | CYP11B1CYP11B2ARTRPV4KDM1A | |
| SCHEMBL9556004 | 0.93 | CYP11B1 (0.38) | CYP11B1CYP11B2ARTRPV4KDM1A | |
| SCHEMBL9556497 | 0.92 | CYP11B1 (0.37) | CYP11B1CYP11B2ARTRPV4KDM1A | |
| SCHEMBL9556494 | 0.92 | CYP11B1 (0.37) | CYP11B1CYP11B2ARTRPV4KDM1A | |
| SCHEMBL10776512 | 0.92 | CYP11B1 (0.37) | CYP11B1CYP11B2ARTRPV4KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4704227-A | DERIVATIVES OF 1,3-DIOXANE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1987-11-03 | — | — | US | disclosed |