Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 14/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4814308 | 0.85 | NISCH (0.46) | NISCHADRA2AADRA2BADRA2C | |
| SCHEMBL4823688 | 0.79 | KCNH2 (0.54) | NISCHPDCD1LG2CD274 | |
| SCHEMBL4821748 | 0.79 | MC4R (0.54) | NISCHADRA2AADRA2BADRA2CPDCD1LG2 | |
| SCHEMBL7594061 | 0.75 | ABCG2 (0.55) | — | |
| SCHEMBL3394014 | 0.74 | NISCH (0.65) | NISCHPDCD1LG2CD274 | |
| SCHEMBL9579892 | 0.73 | NISCH (0.81) | NISCH | |
| SCHEMBL4821355 | 0.73 | MC4R (0.44) | NISCH | |
| SCHEMBL4364788 | 0.71 | NISCH (0.40) | NISCH | |
| SCHEMBL4347210 | 0.70 | RIPK3 (0.56) | ADRA2AADRA2BADRA2C | |
| SCHEMBL22040164 | 0.70 | CHEK1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62099375-A | — | — | None | — | — | JP | disclosed |
| JP-S6299375-A | BENZODIOXOLE DERIVATIVE | KOWA CO | 1987-05-08 | — | — | JP | disclosed |