SCHEMBL10780906

SCHEMBL10780906

CCCCC[C@H]1CC[C@H](c2ccc(C(C)=O)c(F)c2)CC1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.44
MAPT P10636 3/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPK1 P28482 1/20 0.37
RARB P10826 2/20 0.36
RARA P10276 1/20 0.36
RARG P13631 1/20 0.36
TP53 P04637 1/20 0.36
POLB P06746 1/20 0.36
CRBN Q96SW2 2/20 0.35
S1PR1 P21453 2/20 0.35
SGPL1 O95470 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C8 P10632 1/20 0.35
S1PR3 Q99500 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10782375 0.99 CYP2C9 (0.43) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL10782964 0.99 CYP2C9 (0.43) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL10951397 0.96 CYP2C9 (0.45) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL10782396 0.93 CYP2C9 (0.42) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL10783589 0.91 CYP2C9 (0.53) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL8104563 0.90 RARB (0.47) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL5953754 0.90 RARB (0.47) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL9669086 0.89 CYP2C9 (0.43) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL10778701 0.89 RARB (0.49) CYP2C9MAPTALDH1A1LMNARARB
SCHEMBL10778707 0.89 RARB (0.49) CYP2C9MAPTALDH1A1LMNARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0119756-B1 FLUOROBENZENE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE SAME Chisso Corporation (JP) 1987-01-28 EP disclosed
US-4536321-A Fluorobenzene derivatives and liquid crystal compositions containing the same CHISSO CORPORATION (JP) 1985-08-20 US disclosed
EP-0119756-A1 Fluorobenzene derivatives and liquid crystal compositions containing the same Chisso Corporation (JP) 1984-09-26 EP disclosed