Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10785575 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2TP53POLBTHRBL3MBTL1 | |
| SCHEMBL8884143 | 0.81 | CYP3A4 (0.46) | SMN1; SMN2TP53CYP2C19CYP3A4POLB | |
| SCHEMBL10783109 | 0.80 | TP53 (0.50) | SMN1; SMN2TP53CYP2C19CYP3A4POLB | |
| SCHEMBL11123242 | 0.78 | KDM4E (0.54) | SMN1; SMN2TP53CYP2C19CYP3A4POLB | |
| SCHEMBL9023516 | 0.78 | MAPT (0.47) | SMN1; SMN2TP53CYP2C19CYP3A4POLB | |
| SCHEMBL10789204 | 0.78 | EHMT2 (0.51) | SMN1; SMN2TP53POLBAGPAT2L3MBTL1 | |
| SCHEMBL10784705 | 0.77 | GAA (0.57) | SMN1; SMN2POLBL3MBTL1GAAMEN1 | |
| SCHEMBL8884987 | 0.76 | MAPT (0.52) | SMN1; SMN2TP53CYP2C19CYP3A4POLB | |
| SCHEMBL3789310 | 0.73 | NQO1 (0.52) | TP53CYP3A4POLBL3MBTL1GAA | |
| SCHEMBL11521594 | 0.73 | MAPK10 (0.62) | SMN1; SMN2TP53CYP2C19POLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107780-B1 | FLUORAN COMPOUNDS | HODOGAYA CHEMICAL CO., LTD. (JP) | 1987-11-04 | — | — | EP | disclosed |
| US-4594601-A | Fluoran compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| EP-0107780-A2 | Fluoran compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 1984-05-09 | — | — | EP | disclosed |