SCHEMBL10784652

SCHEMBL10784652

CC(C)OC(=O)c1cc(Oc2c(Cl)cc(Cl)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.57
SMN1; SMN2 Q16637 4/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TTR P02766 1/20 0.43
PPOX P50336 1/20 0.43
MAPT P10636 5/20 0.42
PLA2G1B P04054 1/20 0.42
ATG4B Q9Y4P1 1/20 0.42
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
POLB P06746 1/20 0.41
ALDH1A1 P00352 3/20 0.38
MAPK1 P28482 2/20 0.38
TSHR P16473 1/20 0.38
THRA P10827 2/20 0.38
THRB P10828 2/20 0.38
LMNA P02545 2/20 0.37
RAF1 P04049 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10789183 0.93 TDP1 (0.53) TDP1SMN1; SMN2MEN1KMT2ATTR
SCHEMBL11672260 0.88 TDP1 (0.53) TDP1SMN1; SMN2MEN1KMT2ATTR
SCHEMBL10786872 0.87 TDP1 (0.74) TDP1MEN1KMT2ATTRPPOX
SCHEMBL10784983 0.86 TDP1 (0.78) TDP1SMN1; SMN2MEN1KMT2ATTR
SCHEMBL11672378 0.84 TDP1 (0.48) TDP1SMN1; SMN2MEN1KMT2ATTR
SCHEMBL10789155 0.84 TDP1 (0.55) TDP1SMN1; SMN2MEN1KMT2ATTR
SCHEMBL10675388 0.84 TDP1 (0.57) TDP1SMN1; SMN2MEN1KMT2ATTR
SCHEMBL10790720 0.83 TDP1 (0.55) TDP1SMN1; SMN2MEN1KMT2ATTR
SCHEMBL10671694 0.83 TDP1 (0.59) TDP1MEN1KMT2ATTRPPOX
SCHEMBL11673605 0.82 TDP1 (0.48) TDP1SMN1; SMN2MEN1KMT2ATTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4681622-A 2-NITRO-5-(SUBSTITUTED-PHENOXY) BENZOIC ACIDS RHONE-POULENC AGROCHIMIE (FR) 1987-07-21 US disclosed
US-RE32243-E Esters of substituted phenoxybenzoic acids, compositions of the same and herbicidal use thereof RHONE-POULENC AGROCHIMIE (FR) 1986-09-09 US disclosed
US-4606758-A Substituted phenoxybenzoic acids and derivative thereof as herbicides RHONE-POULENC AGROCHIMIE (FR) 1986-08-19 US disclosed
US-RE32216-E Salts of substituted phenoxybenzoic acids, compositions of the same and herbicidal use thereof RHONE-POULENC AGROCHIMIE (FR) 1986-07-29 US disclosed
US-RE32215-E Substituted phenoxybenzoic acids compositions of the same and herbicidal use thereof RHONE-POULENC AGROCHIMIE (FR) 1986-07-22 US disclosed
US-RE31831-E Substituted phenoxybenzoic acids and esters thereof RHONE-POULENC AGROCHIMIE (FR) 1985-02-12 US disclosed
US-4164409-A Substituted phenoxybenzoic acids, compositions of the same and herbicidal use thereof MOBIL OIL CORP. (US) 1979-08-14 US disclosed
US-4164410-A Esters of substituted phenoxybenzoic acids, compositions of the same and herbicidal use thereof MOBIL OIL CORP. (US) 1979-08-14 US disclosed
US-4164408-A Salts of substituted phenoxybenzoic acids, compositions of the same and herbicidal use thereof MOBIL OIL CORP. (US) 1979-08-14 US disclosed
US-4002662-A HERBICIDES MOBIL OIL CORPORATION (US) 1977-01-11 US disclosed
US-3979437-A HERBICIDES MOBIL OIL CORPORATION (US) 1976-09-07 US disclosed
US-3941830-A HERBICIDE MOBIL OIL CORPORATION (US) 1976-03-02 US disclosed