Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 8/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | RARB | P10826 | 5/20 | 0.62 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10785284 | 0.99 | PLA2G4B (0.67) | PLA2G4BTP53TSHRRARBPLA2G4A | |
| SCHEMBL3842241 | 0.90 | PLA2G4B (0.55) | PLA2G4BTP53TSHRRARBPLA2G4A | |
| SCHEMBL5471637 | 0.88 | PLA2G4B (0.60) | PLA2G4BTP53TSHRRARBPLA2G4A | |
| SCHEMBL25788025 | 0.87 | TP53 (0.75) | PLA2G4BTP53TSHRRARBPLA2G4A | |
| SCHEMBL9417076 | 0.86 | PLA2G4B (0.65) | PLA2G4BTP53TSHRRARBPLA2G4A | |
| SCHEMBL8457408 | 0.86 | PLA2G4B (0.65) | PLA2G4BTP53TSHRRARBPLA2G4A | |
| SCHEMBL9574345 | 0.86 | PLA2G4B (0.65) | PLA2G4BTP53TSHRRARBPLA2G4A | |
| SCHEMBL9574428 | 0.86 | PLA2G4B (0.65) | PLA2G4BTP53TSHRRARBPLA2G4A | |
| SCHEMBL9574307 | 0.86 | PLA2G4B (0.65) | PLA2G4BTP53TSHRRARBPLA2G4A | |
| SCHEMBL8457405 | 0.86 | PLA2G4B (0.65) | PLA2G4BTP53TSHRRARBPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4684665-A | Sebosuppressive benzoic acid ester derivatives and cosmetic preparations containing them | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1987-08-04 | — | — | US | disclosed |