Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12944590 | 0.94 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1 | |
| SCHEMBL2182937 | 0.90 | HSP90AA1 (0.51) | HSP90AA1 | |
| SCHEMBL2180278 | 0.90 | HSP90AA1 (0.51) | HSP90AA1 | |
| SCHEMBL1077892 | 0.88 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1 | |
| SCHEMBL1078520 | 0.87 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1 | |
| SCHEMBL463009 | 0.87 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1 | |
| SCHEMBL463010 | 0.87 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1 | |
| SCHEMBL1076054 | 0.86 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1 | |
| SCHEMBL1077518 | 0.83 | HSP90AA1 (0.65) | HSP90AA1 | |
| SCHEMBL2183160 | 0.83 | HSP90AA1 (0.43) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011004132-A1 | NOVEL HSP90-INHIBITING INDOLE DERIVATIVES, COMPOSITIONS CONTAINING SAID DERIVATIVES, AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-01-13 | — | — | WO | disclosed |