SCHEMBL10787115

SCHEMBL10787115

O=C(O)c1ccc(-c2cc(C(=O)O)ccc2C(=O)O)c(C(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.53
TTR P02766 2/20 0.50
PTPRC P08575 2/20 0.48
CYP2C8 P10632 1/20 0.48
CYP2C9 P11712 1/20 0.48
POLB P06746 4/20 0.46
KMT2A Q03164 1/20 0.46
CDC25A P30304 1/20 0.46
CDC25B P30305 1/20 0.46
HSD17B10 Q99714 1/20 0.46
FOLH1 Q04609 2/20 0.45
MYC P01106 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
TSHR P16473 2/20 0.44
TP53 P04637 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141961 0.91 KDM4E (0.55) KDM4ETTRPTPRCCYP2C8CYP2C9
SCHEMBL7633476 0.91 KDM4E (0.55) KDM4ETTRPTPRCCYP2C8CYP2C9
SCHEMBL29699465 0.91 KDM4E (0.55) KDM4ETTRPTPRCCYP2C8CYP2C9
SCHEMBL29370227 0.91 KDM4E (0.55) KDM4ETTRPTPRCCYP2C8CYP2C9
Hydrochloric Acid SCHEMBL28949814 0.89 KDM4E (0.53) KDM4ETTRPTPRCCYP2C8CYP2C9
SCHEMBL10783891 0.87 CSNK2A1 (0.50) KDM4ETTRPTPRCCYP2C8CYP2C9
SCHEMBL29369532 0.86 FOLH1 (0.59) KDM4ETTRPTPRCCYP2C8CYP2C9
SCHEMBL10787725 0.86 TTR (0.58) KDM4ETTRPTPRCCYP2C8CYP2C9
Hypophosphorous Acid SCHEMBL7187710 0.83 KDM4E (0.48) KDM4ETTRPTPRCCYP2C8CYP2C9
SCHEMBL9727757 0.82 KDM4E (0.53) KDM4ETTRCYP2C8CYP2C9POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0052927-B1 STRETCHED FILM STRUCTURE OF THE POLY-1,3-PHENYLENE TEREPHTHALATE TYPE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-01-07 EP disclosed
US-4390683-A Stretched film structure of the poly-1,3-phenylene terephthalate type MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1983-06-28 US disclosed