Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585244 | 0.93 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL107213 | 0.91 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL109047 | 0.91 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL3916955 | 0.90 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL93561 | 0.90 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL221477 | 0.89 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Hydrogen Peroxide SCHEMBL28128571 | 0.88 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL2220386 | 0.88 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL18040479 | 0.87 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL1024880 | 0.86 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059121-A1 | Elastomer Compositions Modified By Silanes | DOW CORNING EUROPE SA (BE) | 2012-03-08 | — | — | US | claimed |
| EP-2424740-A1 | ELASTOMER COMPOSITIONS MODIFIED BY SILANES | Dow Corning Corporation (US) | 2012-03-07 | — | — | EP | claimed |
| WO-2010125123-A1 | ELASTOMER COMPOSITIONS MODIFIED BY SILANES | DOW CORNING CORPORATION (US) | 2010-11-04 | — | — | WO | claimed |