Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10782023 | 0.86 | HTT (0.37) | TSHRLMNAHTTALDH1A1POLB | |
| SCHEMBL10786680 | 0.80 | TSHR (0.56) | TSHRLMNAHTTALDH1A1POLB | |
| SCHEMBL2123106 | 0.79 | CYP1A2 (0.52) | TSHRLMNAHTTALDH1A1CYP1A2 | |
| SCHEMBL9172285 | 0.76 | TSHR (0.59) | TSHRLMNAHTTALDH1A1CYP1A2 | |
| SCHEMBL1821090 | 0.76 | TSHR (0.54) | TSHRLMNAHTTALDH1A1POLB | |
| SCHEMBL14060334 | 0.75 | TSHR (0.57) | TSHRLMNAHTTALDH1A1POLB | |
| SCHEMBL9175089 | 0.75 | TSHR (0.57) | TSHRLMNAHTTALDH1A1CYP1A2 | |
| SCHEMBL3674670 | 0.75 | TSHR (0.47) | TSHRLMNAHTTALDH1A1CYP1A2 | |
| SCHEMBL3674672 | 0.75 | TSHR (0.47) | TSHRLMNAHTTALDH1A1CYP1A2 | |
| SCHEMBL2716313 | 0.75 | TSHR (0.61) | TSHRLMNAHTTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4678804-A | PHYTOPATHOGENS | CHEVRON RESEARCH COMPANY (US) | 1987-07-07 | — | — | US | disclosed |