Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790829 | 0.96 | SMN1; SMN2 (0.44) | MEN1KMT2AHSD17B3HTR7TSHR | |
| SCHEMBL10787328 | 0.96 | MEN1 (0.46) | MEN1KMT2AHSD17B3HTR7TSHR | |
| SCHEMBL10791058 | 0.93 | HSD17B3 (0.51) | MEN1KMT2AHSD17B3HTR7TSHR | |
| SCHEMBL10790545 | 0.92 | MEN1 (0.47) | MEN1KMT2AHSD17B3HTR7TSHR | |
| SCHEMBL10791622 | 0.90 | HSD17B3 (0.51) | MEN1KMT2AHSD17B3HTR7THRB | |
| SCHEMBL10791701 | 0.90 | HSD17B3 (0.51) | MEN1KMT2AHSD17B3HTR7THRB | |
| SCHEMBL10791339 | 0.89 | HSD17B3 (0.48) | MEN1KMT2AHSD17B3HTR7TSHR | |
| SCHEMBL10791002 | 0.89 | HSD17B3 (0.52) | MEN1KMT2AHSD17B3HTR7ATM | |
| SCHEMBL10791272 | 0.89 | HSD17B3 (0.53) | MEN1KMT2AHSD17B3HTR7TSHR | |
| SCHEMBL10790602 | 0.88 | SMN1; SMN2 (0.49) | MEN1KMT2AHSD17B3HTR7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155317-B1 | LIQUID CRYSTAL MIXTURES AND NEW ANISOTROPIC COMPOUNDS THEREFOR | MERCK PATENT GmbH (DE) | 1987-07-08 | — | — | EP | disclosed |